If patients withdraw, critical data Is lost: Rethinking long-term follow-up in C> Trials
C>s have delivered life-changing outcomes, but their long-term success depends on follow-up models that are not meeting the needs of participants and are no longer fit for purpose. Traditional long-term follow-up (LTFU) studies place heavy logistical burdens on patients and sites, leading to low participation rates and knowledge gaps. At least 20% of CAR T-cell therapy patients drop out of studies entirely, and 80% drop by year 5. It’s time to rethink the model. This session explores a digital-first approach to LTFU designed to sustain participant engagement, reduce attrition, and maintain scientific and regulatory rigor over time. Join us to learn how remote and hybrid interaction, seamless transitions from parent trials, and patient-centered data capture can strengthen safety monitoring, improve data quality, and better reflect the real-world impact of advanced therapies.
